Best Bets for NCAA Basketball Picks Against the Spread for Wednesday, February 26

Published 12:23 am Wednesday, February 26, 2025

In one of the many compelling matchups on the college basketball schedule on Wednesday, the Georgetown Hoyas and UConn Huskies hit the court at XL Center, one of the 10 games our computer model recommended in terms of picks against the spread.

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Today’s NCAA Men’s Basketball Picks ATS

ATS Pick: Georgetown +13.5 vs. UConn

  • Matchup: Georgetown Hoyas at UConn Huskies
  • Time: 6:30 p.m. ET
  • Date: February 26
  • Computer Projection: UConn by 6.4 points (Bet now on BetMGM)
  • Spread: UConn (-13.5)
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: East Tennessee State -8.5 vs. Mercer

  • Matchup: Mercer Bears at East Tennessee State Buccaneers
  • Time: 6 p.m. ET
  • Date: February 26
  • Computer Projection: East Tennessee State by 12.6 points (Bet now on BetMGM)
  • Spread: East Tennessee State (-8.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Holy Cross +10.5 vs. Colgate

  • Matchup: Holy Cross Crusaders at Colgate Raiders
  • Time: 7 p.m. ET
  • Date: February 26
  • Computer Projection: Colgate by 6.8 points (Bet now on BetMGM)
  • Spread: Colgate (-10.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Utah +15.5 vs. Arizona

  • Matchup: Utah Utes at Arizona Wildcats
  • Time: 9 p.m. ET
  • Date: February 26
  • Computer Projection: Arizona by 11.9 points (Bet now on BetMGM)
  • Spread: Arizona (-15.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Utah State +4.5 vs. Boise State

  • Matchup: Utah State Aggies at Boise State Broncos
  • Time: 10:30 p.m. ET
  • Date: February 26
  • Computer Projection: Boise State by 1.1 points (Bet now on BetMGM)
  • Spread: Boise State (-4.5)
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

ATS Pick: Temple -1.5 vs. South Florida

  • Matchup: South Florida Bulls at Temple Owls
  • Time: 7 p.m. ET
  • Date: February 26
  • Computer Projection: Temple by 4.7 points (Bet now on BetMGM)
  • Spread: Temple (-1.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Memphis -13.5 vs. Rice

  • Matchup: Rice Owls at Memphis Tigers
  • Time: 8 p.m. ET
  • Date: February 26
  • Computer Projection: Memphis by 16.6 points (Bet now on BetMGM)
  • Spread: Memphis (-13.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Eastern Kentucky +1.5 vs. North Florida

  • Matchup: Eastern Kentucky Colonels at North Florida Ospreys
  • Time: 7 p.m. ET
  • Date: February 26
  • Computer Projection: Eastern Kentucky by 1.6 points (Bet now on BetMGM)
  • Spread: North Florida (-1.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: SMU -3.5 vs. Cal

  • Matchup: SMU Mustangs at California Golden Bears
  • Time: 11 p.m. ET
  • Date: February 26
  • Computer Projection: SMU by 6.6 points (Bet now on BetMGM)
  • Spread: SMU (-3.5)
  • TV Channel: ESPNU
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Lipscomb -19.5 vs. Central Arkansas

  • Matchup: Central Arkansas Bears at Lipscomb Bisons
  • Time: 8 p.m. ET
  • Date: February 26
  • Computer Projection: Lipscomb by 22.2 points (Bet now on BetMGM)
  • Spread: Lipscomb (-19.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

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